With Sheila McClennon. Including: Lindsay Duncan talks about the challenge of playing former prime minister Margaret Thatcher in a new BBC production that dramatises the demise of Britain's first female prime minister. Breast Cancer Screening: According to a recent letter in The Times, many healthy women in this country are receiving unnecessary surgery, chemotherapy and radiotherapy. The 23 signatories say the government is not providing women with all the facts when they go for breast screening and cite research by Peter Gotzsche of the Nordic Cochrane Centre in Copenhagen in support of their claims. Jenni speak to Prof Stephen Duffy and Dr Paul Paroah about the issue. As Nick Clegg approaches fatherhood for the third time, he argues that the recession could provide us with an opportunity to rethink old assumptions about who cares for children. Paraplegic adventurer Karen Darke talks about her recent expedition where she sea-kayaked to the San Rafael glacier in Patagonia and about a new lecture tour she is to begin. We examine a new report from the International Research Unit at the Warwick Business School that has found male actors have longer careers than their female counterparts and ask why so few of the opinion writers in the national newspapers are women.