Journalist Nicky Taylor travels to Amsterdam to investigate the growing debate about the legal classification of cannabis. While there she helps out in a coffee shop that sells the drug, and discovers first hand what the effects of cannabis are on everyday life. Back in the UK Nicky finds out about the genetically modified cannabis skunk, cheap and increasingly sold on the streets. The programme asks whether the drug can make you mad, if it is worse than alcohol and if it is stronger than it used to be. Nicky takes part in a month-long medical trial to find out.