Drama series about Jackie Peyton, a no-nonsense emergency room nurse based in New York who has to balance her frenzied job with a complicated home life. Jackie and her husband Kevin worry that their daughter Grace has an anxiety disorder. Somebody else drinks Jackie's drug-laced coffee. Jackie shifts blame for the resurfaced flushed ear onto rookie Zoey, and must swallow her pride and tell Coop that he had been right about diagnosing a patient's unlikely aneurysm.