Set in noughties Britain, Mouth to Mouth deals with six young adults as they enter their twenties and realise that there is more to status than a Facebook update. Each year-in-the-life episode concentrates on one character's story as their lives intertwine and sometimes collide. Small events have big effects and molehills become mountains, as each of them scrabble to find their way and discover that be it comic, tragic and unpredictable, modern life can be tough. On the surface, Devine Bello is the perfect daughter - a kind, church-going student nurse who would do anything for anyone. But haunted by the death of her best friend's father, Devine has quit nursing and embarked on a secret life as an escort. Free of responsibilities and with a new name, she plays girlfriend to a series of paying men. But when fate leads her into the path of someone really in need, can she turn her back on her past, or is it time to return to the life she knows?