Horizon follows the emotional journey of three young people with currently untreatable conditions to see if within their lifetime, they can be cured. Sophie is desperate to discover if there's a medical breakthrough which will get her walking again - a car crash after celebrating her A level results left her paralysed from the waist down. Anthony's leg was amputated after a rugby accident on the eve of his eighteenth birthday. Will he ever be able to regrow his leg? Father of four Dean is desperate for a cure for his damaged heart to avoid an early death. They've all read the headlines about the astonishing potential of stem cells to heal the body. Now they've been given access to the pioneering scientists who could transform their lives. With so much at stake, each meeting is highly emotional as our three young people find out if science can fix them.