Drama set in early 1950s Alabama. Things are far from harmonious in the small segregated town of Harmony, Alabama, as ageing club owner Tyrone 'Pine Top' Purvis tries to save his failing nightclub, The Honeydripper Lounge, from being taken over by local gangsters. When big-shot guitarist Guitar Sam, specially hired to save the club's fortunes, fails to turn up for a gig, old Pine Top finds himself with no option but to replace him with a young unkown guitarist fresh into town.